Ednra
Defects in EDNRA-mediated signaling have been implicated in a wide range of diseases, including cancer, hypertension, and cardiovascular disorders. Storage: GeneBLAzer® EDNRA HEK 293T DA Cells and EDNRA-NFAT-bla HEK 293T Cells are shipped on dry ice. Store in liquid nitrogen immediately upon receipt or thaw for immediate use.
If you continue, we'll assume that you are happy to receive all cookies. 16.03.2014 The Human Protein Atlas project is funded by the Knut & Alice Wallenberg Foundation. GeneBLAzer EDNRA-NFAT-bla HEK293T cells contain the human Endothelin Type A Recpetor (EDNRA) stably integrated into the CellSensor NFAT-bla HEK293T cell line. CellSensor NFAT-bla HEK293T cells (Cat. no. K1538) contain a beta-lactamase reporter gene under control of … EDNRA_MOUSE Accession i: Q61614 Primary (citable) accession number: Q61614 Secondary accession number(s): O54993, Q91VV2: Entry history i: Integrated into UniProtKB/Swiss-Prot: November 1, 1997: Last sequence update: May 30, 2003: Last modified: December 2, 2020: This is version 172 View mouse Ednra Chr8:77663029-77724452 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression EDNRA DrugBank Gene Name P25101 UniProt Accession 1909 Entrez Gene Id Gene Info: Publications: Martin et al., 2000, Differential effects of the mixed ET(A)/ET(B)-receptor antagonist bosentan on endothelin-induced bronchoconstriction, vasoconstriction and prostacyclin release., Naunyn Schmiedebergs Arch. Pharmacol.
10.06.2021
EDNRA. endothelin receptor type A. This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube. EDNRA gene expression in Bgee. Bgee allows to automatically compare gene expression patterns between species, by referencing expression data on anatomical ontologies, and designing homology relationships between them. Ednra tm1b(EUCOMM)Hmgu: Reporter-tagged deletion allele (post-Cre) Mice Ednra tm1a(EUCOMM)Hmgu: KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells: Ednra tm1(NCOM)Mfgc EDNRA (endothelin A receptor) is a 427 amino acid (aa) protein of the rhodopsin-like 7-transmembrane receptor family.
Ednra endothelin receptor type A [ (house mouse)]. Gene ID: 13617, updated on 18-Jan-2021. Summary. Other designations. endothelin-1 receptor, ET-A,
Validated in WB, IHC, ICC/IF and tested in Mouse, Human. Cited in 10 publication(s).
Expression of EDNRA in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers.
This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system.
COVID-19 is an emerging, rapidly evolving situation. Get the latest public health information from CDC: https EDNRA.
May 01, 1992 · ednra_human
This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Abstract Objective: The most potent vasoconstrictor, endothelin-1 and its receptors, endothelin receptor A (EDNRA) and endothelin receptor B (EDNRB) are involved in hypertension. Hypertension is a major risk factor of intracerebral hemorrhage (ICH). View mouse Ednra Chr8:77663029-77724452 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression
ETA Euzkadi ta Askatsuna: an organization of militant Basque nationalists attempting to gain independence for the Basques, esp those ruled by Spain, until a cease-fire in 1998, by means of guerrilla warfare Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005
View Ednra
Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Background: EDNRA/Endothelin R Type A. EDNRA (endothelin A receptor) is a 427 amino acid (aa) protein of the rhodopsin-like 7-transmembrane receptor family. It can be variably modified by N-linked glycoproteins, phosphorylation and palmitoylation. It binds endothelins ET-1 and ET-2 preferentially, while EDNRB binds all three forms equally. Phenotype data for mouse gene Ednra. Discover Ednra's significant phenotypes, expression, images, histopathology and more.
Gene: EDNRA. GWAS; Genes; EDNRA. EDNRA. Gene information. Gene name.
Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3 (By similarity). Browse information about EDNRA (ENSG00000151617) covering related drugs, protein structure, pathways, genetic associations, orthologs, RNA expression and cancer biomarkers. ednra_human
This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. The following transcription factors affect gene expression: p53; CREB; AP-1; c-Jun; deltaCREB; C/EBPalpha; c-Fos; Tissue specificity: Isoform 1, isoform 3 and isoform 4 are expressed in a variety of tissues, with highest levels in the aorta and cerebellum, followed by lung, atrium and cerebral cortex, lower levels in the placenta, kidney, adrenal gland, duodenum, colon, ventricle and liver but Functional Associations.
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ednra_mouse
This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries.
Go to Variation Viewer for EDNRA variants. Search results for EDNRA at Sigma-Aldrich. Summary: This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. Browse information about EDNRA (ENSG00000151617) covering related drugs, protein structure, pathways, genetic associations, orthologs, RNA expression and … GeneBLAzer® EDNRA HEK 293T DA Cells and EDNRA-NFAT-bla HEK 293T Cells are shipped on dry ice. Store in liquid nitrogen immediately upon receipt or thaw for immediate use.
Ednra endothelin receptor type A [ (house mouse)]. Gene ID: 13617, updated on 18-Jan-2021. Summary. Other designations. endothelin-1 receptor, ET-A,
(1992) determined that the EDNRA gene spans more than 40 kb and contains 8 exons and 7 introns. The transcription start site, determined by primer extension experiments, was 502 bp upstream of the methionine initiation codon. May 01, 1992 · ednra_human
This subsection of the 'Entry information' section provides one or more accession number(s).
GTR Test ID Help Each Test is a specific, orderable test from a particular laboratory, and is assigned a unique GTR accession number.